About Me

I am interested in how computations are performed by networks of neurons with a particular focus on how motor behavior can be produced by circuits in the brain and spinal cord. I founded a company, Cognescent, that is using related ideas to build non-invasive technologies for decoding motor intention. I did my doctoral work in the laboratories of Thomas Jessell and Liam Paninski at Columbia University. I defended my dissertation entitled: "Probing circuits for motor control" in July 2015.

A more complete publication list can be found on my Google Scholar profile. Contact me at first name dot last name at gmail.


Machado, T.A. , Pnevmatikakis, E., Paninski, L., Jessell, T.M., Miri, A. "Primacy of flexor locomotor pattern revealed by ancestral reversion of motor neuron identity" Cell 162: 338-350 (2015) Cover article.
• Pnevmatikakis, E.A., Soudry, D., Gao, Y., Machado, T.A. , Merel, J., Pfau, D., Reardon, T., Mu, Y., Lacefield, C., Yang, W., Ahrens, M., Bruno, R., Jessell T.M., Peterka D.S., Yuste, R., Paninski, L. "Simultaneous denoising, deconvolution, and demixing of calcium imaging data" Neuron 89 (2): 285–299 (2016).
• Rad, K. R., Machado, T.A. , Jessell, T., Paninski, L. "Robust and scalable bayesian analysis of spatial neural data" In press.
• Bikoff, J.B., Gabitto, M.I., Rivard, A.F., Drobac, E., Machado, T.A. , Miri, A., Brenner-Morton, S., Famojure, E., Diaz, C., Alvarez, F.J, Mentis, G.Z., Jessell, T. "Spinal Inhibitory Interneuron Diversity Delineates Variant Motor Microcircuits" Cell 165 (1): 207-219 (2016).
• Buesing, L., Machado, T.A. , Cunningham, J.P., Paninski, L. "Clustered factor analysis of multineuronal spike data" Advances in Neural Information Processing Systems: 3500-3508 (2014)
• Doi, E., Gauthier, J.L., Field, G.D., Shlens, J., Sher, A., Greschner, M., Machado, T.A. , Jepson, L.H., Mathieson, K., Gunning, D.E., Litke, A.M., Paninski, L., Chichilnisky, E.J., Simoncelli, E.P. "Efficient coding of spatial information in the primate retina" Journal of Neuroscience 32 (46): 16256-16264 (2012)
• Vogelstein, J.T., Packer, A.M., Machado, T.A. , Sippy, T., Babadi, B., Yuste, R., Paninski, L. "Fast non-negative deconvolution for spike train inference from population calcium imaging" Journal of Neurophysiology 104 (6): 3691-3704 (2010)
• Field, G.D., Gauthier, J.L., Sher, A., Greschner, M., Machado, T.A. , Jepson, L.H., Shlens, J., Gunning, D.E., Mathieson, K., Dabrowski, W., Paninski, L., Litke, A.M., Chichilnisky, E.J.. "Functional connectivity in the retina at the resolution of photoreceptors" Nature 467 (7316): 673- 677 (2010)